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Partners with HIV took antiretroviral therapy and had a viral load below 200 copies, and couples had anal sex without a condom. To provide more precise estimates of HIV transmission risk in gay couples with a virally suppressed HIV-positive mate, PARTNER2 researchers conducted this new observational analysis from September 2010 to April 2018. Still, the upper 95% confidence interval in gay couples exceeded that in heterosexual couples (0.84 versus 0.46 per 100 couple-years), a finding raising concern about higher transmission risk in gay couples practicing condomless sex. "An undetectable viral load on HIV treatment renders an individual sexually noninfectious," the researchers concluded.Īmong 1166 HIV-different couples in PARTNER1, 11 HIV-negative partners (including 10 gay/bisexual men) picked up HIV, but none of the new infections could be genetically linked to the HIV-positive partner. These PARTNER2 study results confirm findings in PARTNER1, in which 65% of HIV-different couples were heterosexual. In 783 gay male couples tracked for 8 years, no HIV-positive partner with an undetectable viral load infected his HIV-negative sex mate through 77,000 episodes of anal sex without condoms. PARTNER-2 Study No HIV transmissions in 8 years when gay HIV+ partner has undetectable loadĢ2nd International AIDS Conference, Amsterdam, Netherlands, July 23-27, 2018